Cargando…

Alzheimer’s-Related Peptide Amyloid-β Plays a Conserved Role in Angiogenesis

Alzheimer’s disease research has been at an impasse in recent years with lingering questions about the involvement of Amyloid-β (Aβ). Early versions of the amyloid hypothesis considered Aβ something of an undesirable byproduct of APP processing that wreaks havoc on the human neocortex, yet evolution...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cameron, D. Joshua, Galvin, Cooper, Alkam, Tursun, Sidhu, Harpreet, Ellison, John, Luna, Salvadore, Ethell, Douglas W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392248/ https://www.ncbi.nlm.nih.gov/pubmed/22792182 http://dx.doi.org/10.1371/journal.pone.0039598

Ejemplares similares

Amyloid-β and APP Deficiencies Cause Severe Cerebrovascular Defects: Important Work for an Old Villain
por: Luna, Salvadore, et al.
Publicado: (2013)

Women with the Alzheimer's risk marker ApoE4 lose Aβ-specific CD4(+) T cells 10–20 years before men
por: Begum, A N, et al.
Publicado: (2014)

PT716. Treatment with the Chemotherapeutic Drug Methotrexate Impairs Long-Term Potentiation in the Hippocampus
por: Pechnick, Robert, et al.
Publicado: (2016)

Alzheimer’s Amyloid β Peptide Induces Angiogenesis in an Alzheimer’s Disease Model Mouse through Placental Growth Factor and Angiopoietin 2 Expressions
por: Sheikh, Abdullah Md., et al.
Publicado: (2023)

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish
por: Ethell, Douglas W., et al.
Publicado: (2014)

RhoC Mediates Epidermal Growth Factor-Stimulated Migration and Invasion in Head and Neck Squamous Cell Carcinoma
por: Tumur, Zohra, et al.
Publicado: (2015)

Monitoring Alzheimer Amyloid Peptide Aggregation by EPR
por: Sepkhanova, I., et al.
Publicado: (2009)

Paediatric elbow fractures and public play spaces: adherence to standards for children’s playground equipment and surfacing
por: Smith, Jennifer, et al.
Publicado: (2021)

Amyloid Peptide Toxicity in an Animal Model of Alzheimer Disease
por: Gross, Liza
Publicado: (2007)

β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease
por: Sun, Xiaojuan, et al.
Publicado: (2015)

Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease
por: SAIDO, Takaomi C.
Publicado: (2013)

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease
por: Cheignon, C., et al.
Publicado: (2017)

Alignment of Alzheimer’s disease amyloid β-peptide and klotho
por: LEHRER, STEVEN, et al.
Publicado: (2020)

Oxidation of Methionine-35 in Alzheimer’s amyloid-beta peptide and the aggregation of the oxidized peptide
por: Friedemann, Merlin, et al.
Publicado: (2015)

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide
por: Soscia, Stephanie J., et al.
Publicado: (2010)

The β-amyloid peptide compromises Reelin signaling in Alzheimer’s disease
por: Cuchillo-Ibañez, Inmaculada, et al.
Publicado: (2016)

Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease
por: Roda, Alejandro R., et al.
Publicado: (2022)

Platelets in the Alzheimer's Disease Brain: do they Play a Role in Cerebral Amyloid Angiopathy?
por: Kniewallner, Kathrin M., et al.
Publicado: (2015)

Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein
por: Di Scala, Coralie, et al.
Publicado: (2016)

Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer’s disease: two triggers, one disease
por: Ferreira, Sofia, et al.
Publicado: (2020)

Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease
por: Xie, Zhen, et al.
Publicado: (2022)

Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease
por: Canobbio, Ilaria, et al.
Publicado: (2015)

CSF level of β-amyloid peptide predicts mortality in Alzheimer’s disease
por: Boumenir, Adla, et al.
Publicado: (2019)

Aluminium Binding to Modified Amyloid-β Peptides: Implications for Alzheimer’s Disease
por: Mocanu, Cosmin Stefan, et al.
Publicado: (2020)

Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease
por: Biron, Kaan E., et al.
Publicado: (2011)

Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding
por: Bateman, David A, et al.
Publicado: (2007)

Pyroglutamate-Modified Amyloid Beta Peptides: Emerging Targets for Alzheimer´s Disease Immunotherapy
por: Perez-Garmendia, Roxanna, et al.
Publicado: (2013)

Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer’s Disease
por: Yoon, Sang-Sun, et al.
Publicado: (2012)

Cu(II) enhances the effect of Alzheimer’s amyloid-β peptide on microglial activation
por: Yu, Fengxiang, et al.
Publicado: (2015)

Potential Role of Nanoparticles in Treating the Accumulation of Amyloid-Beta Peptide in Alzheimer’s Patients
por: Abbas, Mohamed
Publicado: (2021)

Metal Binding of Alzheimer’s Amyloid-β and Its Effect on Peptide Self-Assembly
por: Abelein, Axel
Publicado: (2023)

A Peptide That Binds Specifically to the β-Amyloid of Alzheimer's Disease: Selection and Assessment of Anti-β-Amyloid Neurotoxic Effects
por: Wang, Fang, et al.
Publicado: (2011)

Brain p3‐Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β‐peptide
por: Hata, Saori, et al.
Publicado: (2023)

Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
por: Yu, W. Haung, et al.
Publicado: (2005)

Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease
por: Gough, Mallory, et al.
Publicado: (2011)

A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide
por: Walsh, Dominic M, et al.
Publicado: (2009)

Effect of Copper and Zinc on the Single Molecule Self-Affinity of Alzheimer’s Amyloid-β Peptides
por: Hane, Francis T., et al.
Publicado: (2016)

Automation vs. Experience: Measuring Alzheimer’s Beta-Amyloid 1–42 Peptide in the CSF
por: Kollhoff, Alexander L., et al.
Publicado: (2018)

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease
por: Brothers, Holly M., et al.
Publicado: (2018)

The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease Pathophysiology
por: Belo, Rita F., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rpocs92igrrp63j0tdj3ul852q