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Bladder Cancer Diagnosis and Identification of Clinically Significant Disease by Combined Urinary Detection of Mcm5 and Nuclear Matrix Protein 22
BACKGROUND: Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22. METHODS: 1677 consecutive patients under inves...
Autores principales: | Kelly, John D., Dudderidge, Tim J., Wollenschlaeger, Alex, Okoturo, Odu, Burling, Keith, Tulloch, Fiona, Halsall, Ian, Prevost, Teresa, Prevost, Andrew Toby, Vasconcelos, Joana C., Robson, Wendy, Leung, Hing Y., Vasdev, Nikhil, Pickard, Robert S., Williams, Gareth H., Stoeber, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392249/ https://www.ncbi.nlm.nih.gov/pubmed/22792272 http://dx.doi.org/10.1371/journal.pone.0040305 |
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