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Intracellular Overexpression of HIV-1 Nef Impairs Differentiation and Maturation of Monocytic Precursors towards Dendritic Cells

Nef functions as an immunosuppressive factor critical for HIV-1 replication, survival and development of AIDS following HIV-1 infection. What effects Nef exerts on differentiation and maturation of monocytes towards dendritic cells (DCs) remains greatly controversial. In this study, we used THP-1 (h...

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Detalles Bibliográficos
Autores principales:	Guo, Yan, Xu, Wen-Wen, Song, Jie, Deng, Wen, Liu, Di-Qiu, Zhang, Hua-Tang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392284/ https://www.ncbi.nlm.nih.gov/pubmed/22808111 http://dx.doi.org/10.1371/journal.pone.0040179

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