Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetase

Leucyl-tRNA synthetase (LeuRS) produces error free leucyl-tRNA(Leu) by coordinating translocation of the 3′ end of (mis-)charged tRNAs from its synthetic site to a separate proof-reading site for editing. Here we report co-crystal structures of the Escherichia coli LeuRS-tRNA(Leu) complex in the ami...

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Detalles Bibliográficos
Autores principales: Palencia, Andrés, Crépin, Thibaut, Vu, Michael T., Lincecum, Tommie L., Martinis, Susan A., Cusack, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392462/
https://www.ncbi.nlm.nih.gov/pubmed/22683997
http://dx.doi.org/10.1038/nsmb.2317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392462/
https://www.ncbi.nlm.nih.gov/pubmed/22683997
http://dx.doi.org/10.1038/nsmb.2317

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