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Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetase
Leucyl-tRNA synthetase (LeuRS) produces error free leucyl-tRNA(Leu) by coordinating translocation of the 3′ end of (mis-)charged tRNAs from its synthetic site to a separate proof-reading site for editing. Here we report co-crystal structures of the Escherichia coli LeuRS-tRNA(Leu) complex in the ami...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392462/ https://www.ncbi.nlm.nih.gov/pubmed/22683997 http://dx.doi.org/10.1038/nsmb.2317 |