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Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice

BACKGROUND: Disrupted-in-Schizophrenia 1 (DISC1) is considered to be a candidate susceptibility gene for psychiatric disorders, including schizophrenia, bipolar disorder, and major depression. A recent study reported that N-ethyl-N-nitrosourea (ENU)-induced mutations in exon 2 of the mouse Disc1 gen...

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Detalles Bibliográficos
Autores principales:	Shoji, Hirotaka, Toyama, Keiko, Takamiya, Yoshihiro, Wakana, Shigeharu, Gondo, Yoichi, Miyakawa, Tsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392730/ https://www.ncbi.nlm.nih.gov/pubmed/22348257 http://dx.doi.org/10.1186/1756-0500-5-108

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