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Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial

INTRODUCTION: The purpose of this study was to determine whether maraviroc, a human CC chemokine receptor 5 (CCR5) antagonist, is safe and effective in the treatment of active rheumatoid arthritis (RA) in patients on background methotrexate (MTX). METHODS: This phase IIa study comprised two distinct...

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Detalles Bibliográficos
Autores principales:	Fleishaker, Dona L, Garcia Meijide, Juan A, Petrov, Andriy, Kohen, Michael David, Wang, Xin, Menon, Sujatha, Stock, Thomas C, Mebus, Charles A, Goodrich, James M, Mayer, Howard B, Zeiher, Bernhardt G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392799/ https://www.ncbi.nlm.nih.gov/pubmed/22251436 http://dx.doi.org/10.1186/ar3685

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