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Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment

INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is found at elevated concentrations in sera of patients with joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). We recently showed that COMP activates complement via the alternative pathway and that COMP-C3b complexes ar...

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Detalles Bibliográficos
Autores principales:	Happonen, Kaisa E, Saxne, Tore, Geborek, Pierre, Andersson, Maria, Bengtsson, Anders A, Hesselstrand, Roger, Heinegård, Dick, Blom, Anna M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392805/ https://www.ncbi.nlm.nih.gov/pubmed/22264230 http://dx.doi.org/10.1186/ar3694

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