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Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis

INTRODUCTION: Interleukin-10 (IL-10) producing B cells, also known as regulatory B (Breg) cells, play a key role in controlling autoimmunity. Our laboratory and others have demonstrated a pivotal role for Bregs in rheumatological disorders, including experimental models of arthritis and lupus. The a...

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Detalles Bibliográficos
Autores principales: Carter, Natalie A, Rosser, Elizabeth C, Mauri, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392827/
https://www.ncbi.nlm.nih.gov/pubmed/22315945
http://dx.doi.org/10.1186/ar3736

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