Cargando…

Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients

PURPOSE: To compare the surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients. DESIGN: Retrospective comparative case series. METHODS: This was a comparative case series of 36 eyes of 36 African Americans and 43 eyes of 43 whites that underwent...

Descripción completa

Detalles Bibliográficos
Autores principales: Salim, Sarwat, Du, Haiming, Boonyaleephan, Sumalee, Wan, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392916/
https://www.ncbi.nlm.nih.gov/pubmed/22791979
http://dx.doi.org/10.2147/OPTH.S32282
_version_ 1782237667925164032
author Salim, Sarwat
Du, Haiming
Boonyaleephan, Sumalee
Wan, Jim
author_facet Salim, Sarwat
Du, Haiming
Boonyaleephan, Sumalee
Wan, Jim
author_sort Salim, Sarwat
collection PubMed
description PURPOSE: To compare the surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients. DESIGN: Retrospective comparative case series. METHODS: This was a comparative case series of 36 eyes of 36 African Americans and 43 eyes of 43 whites that underwent placement of the Ex-PRESS glaucoma filtration device under a partial-thickness scleral flap for uncontrolled glaucoma. All eyes received intraoperative mitomycin C. The primary outcome measures were intraocular pressure (IOP), number of postoperative glaucoma medications, and surgical success. Surgical success was defined as IOP between 5 and 18 mm Hg, with or without glaucoma medications, without further glaucoma surgery, or loss of light perception vision. RESULTS: Average follow-up was 31.9 ± 9.8 (range, 14.6–47) months for African Americans and 30.7 ± 8.6 (range, 14.3–47) months for whites. At 33 months, surgical success was 80.0% in the African American group and 83.3% in the white group (P = 1.00). Reasons for surgical failure included increased IOP (3 eyes, 3.8%), persistent hypotony with maculopathy (1 eye, 1.3%), and further surgery (4 eyes, 5.06%). Compared with preoperative values, the mean postoperative IOP and number of glaucoma medications were significantly reduced in both groups, and no statistical difference was observed between the two groups at 33 months. Postoperative complications were similar in the two groups. CONCLUSIONS: Similar surgical outcomes were observed in African American and white glaucoma patients after implantation of the Ex-PRESS glaucoma filtration device. This latest modification of glaucoma filtration surgery may be a better surgical option for African Americans given its potential advantages of no tissue removal, predictable outcomes related to consistent lumen size and controlled flow, fewer postoperative complications, and overall reduced inflammation.
format Online
Article
Text
id pubmed-3392916
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-33929162012-07-12 Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients Salim, Sarwat Du, Haiming Boonyaleephan, Sumalee Wan, Jim Clin Ophthalmol Original Research PURPOSE: To compare the surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients. DESIGN: Retrospective comparative case series. METHODS: This was a comparative case series of 36 eyes of 36 African Americans and 43 eyes of 43 whites that underwent placement of the Ex-PRESS glaucoma filtration device under a partial-thickness scleral flap for uncontrolled glaucoma. All eyes received intraoperative mitomycin C. The primary outcome measures were intraocular pressure (IOP), number of postoperative glaucoma medications, and surgical success. Surgical success was defined as IOP between 5 and 18 mm Hg, with or without glaucoma medications, without further glaucoma surgery, or loss of light perception vision. RESULTS: Average follow-up was 31.9 ± 9.8 (range, 14.6–47) months for African Americans and 30.7 ± 8.6 (range, 14.3–47) months for whites. At 33 months, surgical success was 80.0% in the African American group and 83.3% in the white group (P = 1.00). Reasons for surgical failure included increased IOP (3 eyes, 3.8%), persistent hypotony with maculopathy (1 eye, 1.3%), and further surgery (4 eyes, 5.06%). Compared with preoperative values, the mean postoperative IOP and number of glaucoma medications were significantly reduced in both groups, and no statistical difference was observed between the two groups at 33 months. Postoperative complications were similar in the two groups. CONCLUSIONS: Similar surgical outcomes were observed in African American and white glaucoma patients after implantation of the Ex-PRESS glaucoma filtration device. This latest modification of glaucoma filtration surgery may be a better surgical option for African Americans given its potential advantages of no tissue removal, predictable outcomes related to consistent lumen size and controlled flow, fewer postoperative complications, and overall reduced inflammation. Dove Medical Press 2012 2012-06-22 /pmc/articles/PMC3392916/ /pubmed/22791979 http://dx.doi.org/10.2147/OPTH.S32282 Text en © 2012 Salim et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Salim, Sarwat
Du, Haiming
Boonyaleephan, Sumalee
Wan, Jim
Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title_full Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title_fullStr Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title_full_unstemmed Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title_short Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients
title_sort surgical outcomes of the ex-press glaucoma filtration device in african american and white glaucoma patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392916/
https://www.ncbi.nlm.nih.gov/pubmed/22791979
http://dx.doi.org/10.2147/OPTH.S32282
work_keys_str_mv AT salimsarwat surgicaloutcomesoftheexpressglaucomafiltrationdeviceinafricanamericanandwhiteglaucomapatients
AT duhaiming surgicaloutcomesoftheexpressglaucomafiltrationdeviceinafricanamericanandwhiteglaucomapatients
AT boonyaleephansumalee surgicaloutcomesoftheexpressglaucomafiltrationdeviceinafricanamericanandwhiteglaucomapatients
AT wanjim surgicaloutcomesoftheexpressglaucomafiltrationdeviceinafricanamericanandwhiteglaucomapatients