Cargando…

Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells

Addition of actin monomer (G-actin) to growing actin filaments (F-actin) at the leading edge generates force for cell locomotion. The polymerization reaction and its regulation have been studied in depth. However, the mechanism responsible for transport of G-actin substrate to the cell front is larg...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Yi, Eswarappa, Sandeepa M., Hitomi, Masahiro, Fox, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392929/
https://www.ncbi.nlm.nih.gov/pubmed/22778278
http://dx.doi.org/10.1083/jcb.201111088