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Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells
Addition of actin monomer (G-actin) to growing actin filaments (F-actin) at the leading edge generates force for cell locomotion. The polymerization reaction and its regulation have been studied in depth. However, the mechanism responsible for transport of G-actin substrate to the cell front is larg...
Autores principales: | Fan, Yi, Eswarappa, Sandeepa M., Hitomi, Masahiro, Fox, Paul L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392929/ https://www.ncbi.nlm.nih.gov/pubmed/22778278 http://dx.doi.org/10.1083/jcb.201111088 |
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