Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis

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Apoptosis is an essential step in cavitation during embryonic epithelial morphogenesis, but its mechanisms are largely unknown. In this paper, we used embryonic stem cell–differentiated embryoid bodies (EBs) as a model and found that Bnip3 (Bcl-2/adenovirus E1B 19-kD interacting protein), a BH3-only...

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Detalles Bibliográficos
Autores principales: Qi, Yanmei, Tian, Xiaoxiang, Liu, Jie, Han, Yaling, Graham, Alan M., Simon, M. Celeste, Penninger, Josef M., Carmeliet, Peter, Li, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392936/
https://www.ncbi.nlm.nih.gov/pubmed/22753893
http://dx.doi.org/10.1083/jcb.201111063

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