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Acute promyelocytic leukemia, arsenic, and PML bodies

Acute promyelocytic leukemia (APL) is driven by a chromosomal translocation whose product, the PML/retinoic acid (RA) receptor α (RARA) fusion protein, affects both nuclear receptor signaling and PML body assembly. Dissection of APL pathogenesis has led to the rediscovery of PML bodies and revealed...

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Detalles Bibliográficos
Autores principales:	de Thé, Hugues, Le Bras, Morgane, Lallemand-Breitenbach, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392943/ https://www.ncbi.nlm.nih.gov/pubmed/22778276 http://dx.doi.org/10.1083/jcb.201112044

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