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c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

The AP-1 transcription factor c-Jun is a master regulator of the axonal response in neurons. c-Jun also functions as a negative regulator of myelination in Schwann cells (SCs) and is strongly reactivated in SCs upon axonal injury. We demonstrate here that, after injury, the absence of c-Jun specific...

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Detalles Bibliográficos
Autores principales:	Fontana, Xavier, Hristova, Mariya, Da Costa, Clive, Patodia, Smriti, Thei, Laura, Makwana, Milan, Spencer-Dene, Bradley, Latouche, Morwena, Mirsky, Rhona, Jessen, Kristjan R., Klein, Rüdiger, Raivich, Gennadij, Behrens, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392945/ https://www.ncbi.nlm.nih.gov/pubmed/22753894 http://dx.doi.org/10.1083/jcb.201205025

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