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2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph
In the crystal structure of the title compound, C(16)H(14)F(3)N(3)OS·C(3)H(8)O, the molecules are linked into chains along [010] via N—H⋯O and O—H⋯N hydrogen bonds. The triclinic form was reported by Ren et al. [(2011). Acta Cryst. E67, o270] and the first monoclinic form by Chen et al. [(2012). Ac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393286/ https://www.ncbi.nlm.nih.gov/pubmed/22807843 http://dx.doi.org/10.1107/S1600536812022143 |
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| author | Ma, Jin-Ju Qi, Ming-Hui Hong, Ming-Huang Lu, Jie Ren, Guo-Bin |
| author_facet | Ma, Jin-Ju Qi, Ming-Hui Hong, Ming-Huang Lu, Jie Ren, Guo-Bin |
| author_sort | Ma, Jin-Ju |
| collection | PubMed |
| description | In the crystal structure of the title compound, C(16)H(14)F(3)N(3)OS·C(3)H(8)O, the molecules are linked into chains along [010] via N—H⋯O and O—H⋯N hydrogen bonds. The triclinic form was reported by Ren et al. [(2011). Acta Cryst. E67, o270] and the first monoclinic form by Chen et al. [(2012). Acta Cryst. E68, o2015–o2016]. The fused five-and six-membered rings make a dihedral angle of 1.22 (2)°, while the benzene and pyridine rings make a dihedral angle of 10.15 (2)°. |
| format | Online Article Text |
| id | pubmed-3393286 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33932862012-07-17 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph Ma, Jin-Ju Qi, Ming-Hui Hong, Ming-Huang Lu, Jie Ren, Guo-Bin Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(16)H(14)F(3)N(3)OS·C(3)H(8)O, the molecules are linked into chains along [010] via N—H⋯O and O—H⋯N hydrogen bonds. The triclinic form was reported by Ren et al. [(2011). Acta Cryst. E67, o270] and the first monoclinic form by Chen et al. [(2012). Acta Cryst. E68, o2015–o2016]. The fused five-and six-membered rings make a dihedral angle of 1.22 (2)°, while the benzene and pyridine rings make a dihedral angle of 10.15 (2)°. International Union of Crystallography 2012-06-13 /pmc/articles/PMC3393286/ /pubmed/22807843 http://dx.doi.org/10.1107/S1600536812022143 Text en © Ma et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Ma, Jin-Ju Qi, Ming-Hui Hong, Ming-Huang Lu, Jie Ren, Guo-Bin 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title | 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title_full | 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title_fullStr | 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title_full_unstemmed | 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title_short | 2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1H-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| title_sort | 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl}-1h-benzimidazole propan-2-ol monosolvate: a second monoclinic polymorph |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393286/ https://www.ncbi.nlm.nih.gov/pubmed/22807843 http://dx.doi.org/10.1107/S1600536812022143 |
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