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Ethyl 2-(pyridine-4-carboxamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
In the title compound, C(17)H(18)N(2)O(3)S, the dihedral angles between the thiophene ring and the ethyl ester group and the pyridine-4-carboxamide unit are 7.1 (2) and 9.47 (11)°, respectively. An intramolecular N—H⋯O hydrogen bond generates an S(6) ring. In the crystal, inversion dimers linked b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393309/ https://www.ncbi.nlm.nih.gov/pubmed/22807866 http://dx.doi.org/10.1107/S1600536812025251 |
Sumario: | In the title compound, C(17)H(18)N(2)O(3)S, the dihedral angles between the thiophene ring and the ethyl ester group and the pyridine-4-carboxamide unit are 7.1 (2) and 9.47 (11)°, respectively. An intramolecular N—H⋯O hydrogen bond generates an S(6) ring. In the crystal, inversion dimers linked by pairs of C—H⋯O hydrogen bonds between the tetrahydro-1-benzothiophene and the pyridine-4-carboxamide residues generate R (2) (2)(16) loops. There exists positional disorder in three methelene groups of the cyclohexane ring and the terminal C atom of the ethyl ester side chain in a 0.691 (14):0.309 (14) occupancy ratio. |
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