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4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy
We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393348/ https://www.ncbi.nlm.nih.gov/pubmed/22843630 http://dx.doi.org/10.1093/jrr/rrs013 |
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author | Nakagawa, Keiichi Kida, Satoshi Haga, Akihiro Masutani, Yoshitaka Yamashita, Hideomi Onoe, Tsuyoshi Imae, Toshikazu Tanaka, Kenichiro Ohtomo, Kuni Yoda, Kiyoshi |
author_facet | Nakagawa, Keiichi Kida, Satoshi Haga, Akihiro Masutani, Yoshitaka Yamashita, Hideomi Onoe, Tsuyoshi Imae, Toshikazu Tanaka, Kenichiro Ohtomo, Kuni Yoda, Kiyoshi |
author_sort | Nakagawa, Keiichi |
collection | PubMed |
description | We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acquired by 4D planning computed tomography (CT). A planning target volume (PTV) was defined by adding a margin of 5 mm to the ITV on the maximum exhalation 3D CT images. A single-arc VMAT plan was created on the same CT data using Pinnacle SmartArc with a maximum multi-leaf collimator leaf speed of 1 mm/degree, thereby resulting in quasi-conformal field shapes while optimizing each beam intensity for each gantry angle. During VMAT delivery, cone-beam CT (CBCT) projection data were acquired by an on-board kilovoltage X-ray unit and a flat panel 2D detector. Four CBCT image sets with different respiratory phases were reconstructed using in-house software, where respiratory phases were extracted from the projection data. Subsequently a CTV was delineated on each of the 4D CBCT images by an oncologist. Using the resulting 4D CBCT data including the CTV contours, 4D DRRs during the VMAT delivery were calculated as a function of gantry angle. It was confirmed that the contoured CTV was within the radiation field during the four-fraction lung VMAT delivery. The proposed 4D DRR may facilitate the verification of the position of a respiratory moving lung tumor during VMAT delivery on each treatment day. |
format | Online Article Text |
id | pubmed-3393348 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-33933482013-07-01 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy Nakagawa, Keiichi Kida, Satoshi Haga, Akihiro Masutani, Yoshitaka Yamashita, Hideomi Onoe, Tsuyoshi Imae, Toshikazu Tanaka, Kenichiro Ohtomo, Kuni Yoda, Kiyoshi J Radiat Res Short Communications We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acquired by 4D planning computed tomography (CT). A planning target volume (PTV) was defined by adding a margin of 5 mm to the ITV on the maximum exhalation 3D CT images. A single-arc VMAT plan was created on the same CT data using Pinnacle SmartArc with a maximum multi-leaf collimator leaf speed of 1 mm/degree, thereby resulting in quasi-conformal field shapes while optimizing each beam intensity for each gantry angle. During VMAT delivery, cone-beam CT (CBCT) projection data were acquired by an on-board kilovoltage X-ray unit and a flat panel 2D detector. Four CBCT image sets with different respiratory phases were reconstructed using in-house software, where respiratory phases were extracted from the projection data. Subsequently a CTV was delineated on each of the 4D CBCT images by an oncologist. Using the resulting 4D CBCT data including the CTV contours, 4D DRRs during the VMAT delivery were calculated as a function of gantry angle. It was confirmed that the contoured CTV was within the radiation field during the four-fraction lung VMAT delivery. The proposed 4D DRR may facilitate the verification of the position of a respiratory moving lung tumor during VMAT delivery on each treatment day. Oxford University Press 2012-07 /pmc/articles/PMC3393348/ /pubmed/22843630 http://dx.doi.org/10.1093/jrr/rrs013 Text en © The Author 2012. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology. http://creativecommons.org/licenses/by-nc/2.5/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communications Nakagawa, Keiichi Kida, Satoshi Haga, Akihiro Masutani, Yoshitaka Yamashita, Hideomi Onoe, Tsuyoshi Imae, Toshikazu Tanaka, Kenichiro Ohtomo, Kuni Yoda, Kiyoshi 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title | 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title_full | 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title_fullStr | 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title_full_unstemmed | 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title_short | 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
title_sort | 4d digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy |
topic | Short Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393348/ https://www.ncbi.nlm.nih.gov/pubmed/22843630 http://dx.doi.org/10.1093/jrr/rrs013 |
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