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Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin

BACKGROUND: Epidemiological studies revealed a strong correlation between the metabolic syndrome/diabetes mellitus type 2 (DM2) and higher incidence and faster progression of breast and colon cancer. However, the underlying molecular mechanisms are widely unknown. Akt and phospholipase Cγ (PLCγ) are...

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Detalles Bibliográficos
Autores principales:	Tomas, Nicola M, Masur, Kai, Piecha, Jonas C, Niggemann, Bernd, Zänker, Kurt S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393613/ https://www.ncbi.nlm.nih.gov/pubmed/22554284 http://dx.doi.org/10.1186/1756-0500-5-214

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