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Insights into dynein motor domain function from a 3.3 Å crystal structure

Dyneins power the beating of cilia and flagella, transport various intracellular cargos and are important during mitosis. All dyneins have a ~300kDa motor domain consisting of a ring of six AAA+ domains. ATP hydrolysis in the AAA+ ring drives the cyclic relocation of a motile element, the linker dom...

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Detalles Bibliográficos
Autores principales:	Schmidt, Helgo, Gleave, Emma S., Carter, Andrew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393637/ https://www.ncbi.nlm.nih.gov/pubmed/22426545 http://dx.doi.org/10.1038/nsmb.2272

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