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Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer

In the present study, we have taken the novel approach of using an in vitro model representative of tamoxifen-withdrawal subsequent to clinical relapse to achieve a greater understanding of the mechanisms that serve to maintain the resistant-cell phenotype, independent of any agonistic impact of tam...

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Detalles Bibliográficos
Autores principales:	Stone, Andrew, Valdés-Mora, Fatima, Gee, Julia M. W., Farrow, Lynne, McClelland, Richard A., Fiegl, Heidi, Dutkowski, Carol, McCloy, Rachael A., Sutherland, Robert L., Musgrove, Elizabeth A., Nicholson, Robert I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393679/ https://www.ncbi.nlm.nih.gov/pubmed/22808167 http://dx.doi.org/10.1371/journal.pone.0040466

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