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Campylobacter jejuni Induces Acute Enterocolitis in Gnotobiotic IL-10(−/−) Mice via Toll-Like-Receptor-2 and -4 Signaling
BACKGROUND: Campylobacter jejuni is a leading cause of foodborne bacterial enterocolitis worldwide. Investigation of immunopathology is hampered by a lack of suitable vertebrate models. We have recently shown that gnotobiotic mice as well as conventional IL-10(−/−) animals are susceptible to C. jeju...
Autores principales: | Haag, Lea-Maxie, Fischer, André, Otto, Bettina, Plickert, Rita, Kühl, Anja A., Göbel, Ulf B., Bereswill, Stefan, Heimesaat, Markus M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393706/ https://www.ncbi.nlm.nih.gov/pubmed/22808254 http://dx.doi.org/10.1371/journal.pone.0040761 |
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