An Improved Genetically Encoded Red Fluorescent Ca(2+) Indicator for Detecting Optically Evoked Action Potentials

Genetically encoded Ca(2+) indicators (GECIs) are powerful tools to image activities of defined cell populations. Here, we developed an improved red fluorescent GECI, termed R-CaMP1.07, by mutagenizing R-GECO1. In HeLa cell assays, R-CaMP1.07 exhibited a 1.5–2-fold greater fluorescence response comp...

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Detalles Bibliográficos
Autores principales: Ohkura, Masamichi, Sasaki, Takuya, Kobayashi, Chiaki, Ikegaya, Yuji, Nakai, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393713/
https://www.ncbi.nlm.nih.gov/pubmed/22808076
http://dx.doi.org/10.1371/journal.pone.0039933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393713/
https://www.ncbi.nlm.nih.gov/pubmed/22808076
http://dx.doi.org/10.1371/journal.pone.0039933

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