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Antibody-Antigen-Adjuvant Conjugates Enable Co-Delivery of Antigen and Adjuvant to Dendritic Cells in Cis but Only Have Partial Targeting Specificity

Antibody-antigen conjugates, which promote antigen-presentation by dendritic cells (DC) by means of targeted delivery of antigen to particular DC subsets, represent a powerful vaccination approach. To ensure immunity rather than tolerance induction the co-administration of a suitable adjuvant is par...

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Detalles Bibliográficos
Autores principales:	Kreutz, Martin, Giquel, Benoit, Hu, Qin, Abuknesha, Ram, Uematsu, Satoshi, Akira, Shizuo, Nestle, Frank O., Diebold, Sandra S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393736/ https://www.ncbi.nlm.nih.gov/pubmed/22808118 http://dx.doi.org/10.1371/journal.pone.0040208

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