8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one

The title compound, C(21)H(23)NO(3), is a phenyl­imine derivative of the well known anthelmintic agent α-santonin. The trans-fused cyclo­hexane and γ-lactone rings of the α-santonin ring system adopt chair and envelope conformations, respectively, whereas the hexa­diene ring is approximately planar...

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Detalles Bibliográficos
Autores principales: Yousuf, Sammer, Younas, Syed M., Ambreen, Nida, Khan, Khalid M., Miana, Ghulam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393965/
https://www.ncbi.nlm.nih.gov/pubmed/22798830
http://dx.doi.org/10.1107/S1600536812027146
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author Yousuf, Sammer
Younas, Syed M.
Ambreen, Nida
Khan, Khalid M.
Miana, Ghulam A.
author_facet Yousuf, Sammer
Younas, Syed M.
Ambreen, Nida
Khan, Khalid M.
Miana, Ghulam A.
author_sort Yousuf, Sammer
collection PubMed
description The title compound, C(21)H(23)NO(3), is a phenyl­imine derivative of the well known anthelmintic agent α-santonin. The trans-fused cyclo­hexane and γ-lactone rings of the α-santonin ring system adopt chair and envelope conformations, respectively, whereas the hexa­diene ring is approximately planar [maximum deviation = 0.029 (4) Å] and forms a dihedral angle of 62.30 (11)° with the benzene ring. An intra­molecular O—H⋯N hydrogen bond is observed.
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spelling pubmed-33939652012-07-13 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one Yousuf, Sammer Younas, Syed M. Ambreen, Nida Khan, Khalid M. Miana, Ghulam A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(23)NO(3), is a phenyl­imine derivative of the well known anthelmintic agent α-santonin. The trans-fused cyclo­hexane and γ-lactone rings of the α-santonin ring system adopt chair and envelope conformations, respectively, whereas the hexa­diene ring is approximately planar [maximum deviation = 0.029 (4) Å] and forms a dihedral angle of 62.30 (11)° with the benzene ring. An intra­molecular O—H⋯N hydrogen bond is observed. International Union of Crystallography 2012-06-20 /pmc/articles/PMC3393965/ /pubmed/22798830 http://dx.doi.org/10.1107/S1600536812027146 Text en © Yousuf et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yousuf, Sammer
Younas, Syed M.
Ambreen, Nida
Khan, Khalid M.
Miana, Ghulam A.
8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title_full 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title_fullStr 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title_full_unstemmed 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title_short 8-[(2-Hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3H)-one
title_sort 8-[(2-hy­droxy­phen­yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa­hydro­naphtho­[1,2-b]furan-2(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393965/
https://www.ncbi.nlm.nih.gov/pubmed/22798830
http://dx.doi.org/10.1107/S1600536812027146
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