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11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione
In the title compound, C(30)H(27)N(3)O(6), the furan and pyrrolidine rings adopt envelope conformations (with C and N atoms as the flaps, respectively). The piperidine ring is in a distorted boat conformation. The β-lactam ring is planar [maximum deviation = 0.0044 (16) Å] and forms dihedral angles...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393999/ https://www.ncbi.nlm.nih.gov/pubmed/22798864 http://dx.doi.org/10.1107/S160053681202733X |
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author | Sundaramoorthy, S. Rajesh, R. Raghunathan, R. Velmurugan, D. |
author_facet | Sundaramoorthy, S. Rajesh, R. Raghunathan, R. Velmurugan, D. |
author_sort | Sundaramoorthy, S. |
collection | PubMed |
description | In the title compound, C(30)H(27)N(3)O(6), the furan and pyrrolidine rings adopt envelope conformations (with C and N atoms as the flaps, respectively). The piperidine ring is in a distorted boat conformation. The β-lactam ring is planar [maximum deviation = 0.0044 (16) Å] and forms dihedral angles of 30.61 (9) and 85.51 (9)°, respectively, with the attached methoxyphenyl and phenoxy rings. The crystal packing is stabilized by N—H⋯O and C—H⋯O interactions forming R (2) (2)(8), R (2) (2)(20) and R (2) (2)(14) ring motifs. The crystal structure is further consolidated by weak C—H⋯π interactions. |
format | Online Article Text |
id | pubmed-3393999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-33939992012-07-13 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione Sundaramoorthy, S. Rajesh, R. Raghunathan, R. Velmurugan, D. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(30)H(27)N(3)O(6), the furan and pyrrolidine rings adopt envelope conformations (with C and N atoms as the flaps, respectively). The piperidine ring is in a distorted boat conformation. The β-lactam ring is planar [maximum deviation = 0.0044 (16) Å] and forms dihedral angles of 30.61 (9) and 85.51 (9)°, respectively, with the attached methoxyphenyl and phenoxy rings. The crystal packing is stabilized by N—H⋯O and C—H⋯O interactions forming R (2) (2)(8), R (2) (2)(20) and R (2) (2)(14) ring motifs. The crystal structure is further consolidated by weak C—H⋯π interactions. International Union of Crystallography 2012-06-23 /pmc/articles/PMC3393999/ /pubmed/22798864 http://dx.doi.org/10.1107/S160053681202733X Text en © Sundaramoorthy et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Sundaramoorthy, S. Rajesh, R. Raghunathan, R. Velmurugan, D. 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title | 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title_full | 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title_fullStr | 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title_full_unstemmed | 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title_short | 11-[1-(4-Methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
title_sort | 11-[1-(4-methoxyphenyl)-4-oxo-3-phenoxyazetidin-2-yl]-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393999/ https://www.ncbi.nlm.nih.gov/pubmed/22798864 http://dx.doi.org/10.1107/S160053681202733X |
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