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2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine

In the title compound, C(20)H(18)BrN(5), the bromo­phenyl-substituted quinazoline unit is essentially planar [maximum deviation = 0.098 (3) Å] and makes a dihedral angle of 56.04 (14)° with the imidazole ring. In the crystal, mol­ecules are associated by pairs of N—H⋯N hydrogen bonds to form inversi...

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Autores principales: Pérez-Fehrmann, Marcia, Kesternich, Victor, Verdugo, Felipe, Christen, Philippe, Besnard, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394037/
https://www.ncbi.nlm.nih.gov/pubmed/22798902
http://dx.doi.org/10.1107/S1600536812028115
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author Pérez-Fehrmann, Marcia
Kesternich, Victor
Verdugo, Felipe
Christen, Philippe
Besnard, Céline
author_facet Pérez-Fehrmann, Marcia
Kesternich, Victor
Verdugo, Felipe
Christen, Philippe
Besnard, Céline
author_sort Pérez-Fehrmann, Marcia
collection PubMed
description In the title compound, C(20)H(18)BrN(5), the bromo­phenyl-substituted quinazoline unit is essentially planar [maximum deviation = 0.098 (3) Å] and makes a dihedral angle of 56.04 (14)° with the imidazole ring. In the crystal, mol­ecules are associated by pairs of N—H⋯N hydrogen bonds to form inversion dimers. All the quinazoline planar systems are oriented almost perpendicular to the [110] direction, making π–π inter­actions possible between adjacent dimers [centroid–centroid distances = 3.7674 (16) and 3.7612 (17) Å]. There are also a number of C—H⋯π inter­actions present. The crystal is a nonmerohedral twin, with a minor twin fraction of 0.47.
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spelling pubmed-33940372012-07-13 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine Pérez-Fehrmann, Marcia Kesternich, Victor Verdugo, Felipe Christen, Philippe Besnard, Céline Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(18)BrN(5), the bromo­phenyl-substituted quinazoline unit is essentially planar [maximum deviation = 0.098 (3) Å] and makes a dihedral angle of 56.04 (14)° with the imidazole ring. In the crystal, mol­ecules are associated by pairs of N—H⋯N hydrogen bonds to form inversion dimers. All the quinazoline planar systems are oriented almost perpendicular to the [110] direction, making π–π inter­actions possible between adjacent dimers [centroid–centroid distances = 3.7674 (16) and 3.7612 (17) Å]. There are also a number of C—H⋯π inter­actions present. The crystal is a nonmerohedral twin, with a minor twin fraction of 0.47. International Union of Crystallography 2012-06-30 /pmc/articles/PMC3394037/ /pubmed/22798902 http://dx.doi.org/10.1107/S1600536812028115 Text en © Pérez-Fehrmann et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Pérez-Fehrmann, Marcia
Kesternich, Victor
Verdugo, Felipe
Christen, Philippe
Besnard, Céline
2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title_full 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title_fullStr 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title_full_unstemmed 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title_short 2-(4-Bromo­phen­yl)-N-[3-(1H-imidazol-1-yl)prop­yl]quinazolin-4-amine
title_sort 2-(4-bromo­phen­yl)-n-[3-(1h-imidazol-1-yl)prop­yl]quinazolin-4-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394037/
https://www.ncbi.nlm.nih.gov/pubmed/22798902
http://dx.doi.org/10.1107/S1600536812028115
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