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4-(3-Phenyl-3,3a,4,5-tetra­hydro-2H-benzo[g]indazol-2-yl)benzene­sulfonamide ethanol monosolvate

In the title compound ethanol monosolvate, C(23)H(21)N(3)O(2)S·C(2)H(5)OH, the dihydro­pyrazole ring is twisted about the Csp (3)—Csp (3) bond. Nevertheless, the ring approximates a plane (r.m.s. deviation for the fitted atoms = 0.132 Å) and forms dihedral angles of 5.80 (13) and 12.29 (12)°, respec...

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Detalles Bibliográficos
Autores principales: Asiri, Abdullah M., Faidallah, Hassan M., Alamry, Khalid A., Ng, Seik Weng, Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394043/
https://www.ncbi.nlm.nih.gov/pubmed/22798908
http://dx.doi.org/10.1107/S1600536812028474
Descripción
Sumario:In the title compound ethanol monosolvate, C(23)H(21)N(3)O(2)S·C(2)H(5)OH, the dihydro­pyrazole ring is twisted about the Csp (3)—Csp (3) bond. Nevertheless, the ring approximates a plane (r.m.s. deviation for the fitted atoms = 0.132 Å) and forms dihedral angles of 5.80 (13) and 12.29 (12)°, respectively, with the fused- and sulfonamide-benzene rings. As the dihydro­pyrazole C-bound phenyl group is roughly perpendicular to the dihydro­pyrazole ring [dihedral angle = 74.04 (15)°; the amino group is orientated to the same side of the mol­ecule], to a first approximation, the mol­ecule has a stunted T-shape. The cyclo­hexene ring adopts a half-chair conformation with the methyl­ene C atom connected to the dihydro­pyrazole ring lying 0.665 (4) Å out of the plane of the five remaining atoms (r.m.s. deviation = 0.050 Å). The components of the asymmetric unit are connected by an O—H⋯O hydrogen bond. Further links between mol­ecules leading to a three-dimensional architecture are of the type N—H⋯O.