Ethyl 4-[({[(6-chloro­pyridin-3-yl)meth­yl](meth­yl)amino}(4-fluoro­anilino)­methyl­idene)amino]-3-phenyl-2-sulfanyl­idene-2,3-dihydro-1,3-thia­zole-5-carboxyl­ate

In the title compound, C(26)H(23)ClFN(5)O(2)S(2), the mean plane of the guanidine fragment makes dihedral angles of 58.94 (13), 78.37 (17) and 50.76 (15)°, respectively, with the attached thia­zole, pyridine and phenyl rings. The crystal structure features N—H⋯S and C—H⋯O hydrogen bonds and weak π–π...

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Detalles Bibliográficos
Autores principales: He, Hai-Feng, He, Hong-Wu, Liang, Ying, Yang, Zi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394060/
https://www.ncbi.nlm.nih.gov/pubmed/22798925
http://dx.doi.org/10.1107/S1600536812026311
Descripción
Sumario:In the title compound, C(26)H(23)ClFN(5)O(2)S(2), the mean plane of the guanidine fragment makes dihedral angles of 58.94 (13), 78.37 (17) and 50.76 (15)°, respectively, with the attached thia­zole, pyridine and phenyl rings. The crystal structure features N—H⋯S and C—H⋯O hydrogen bonds and weak π–π stacking inter­actions [centroid–centroid separation = 3.7702 (17) Å]. The terminal methyl group of the eth­oxy­carbonyl group is disordered over two orientations in a 0.836 (10):0.164 (10) ratio.

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