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1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine
Two independent molecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394077/ https://www.ncbi.nlm.nih.gov/pubmed/22798942 http://dx.doi.org/10.1107/S1600536812029212 |
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author | Ramalingan, Chennan Ng, Seik Weng Tiekink, Edward R. T. |
author_facet | Ramalingan, Chennan Ng, Seik Weng Tiekink, Edward R. T. |
author_sort | Ramalingan, Chennan |
collection | PubMed |
description | Two independent molecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the benzyl residue and one methyl group substituents occupies an equatorial position, and the second methyl substituent occupies an axial position. The dihedral angle formed between the chlorobenzene ring and the flanking phenyl rings in molecule A are 84.24 (9) and 24.85 (8)°; the equivalent angles for molecule B are 79.97 (9) and 28.33 (9)°. In the crystal, the A and B molecules are connected by C—H⋯Cl and C—H⋯π interactions, forming a supramolecular chain along [101]. |
format | Online Article Text |
id | pubmed-3394077 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-33940772012-07-13 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine Ramalingan, Chennan Ng, Seik Weng Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers Two independent molecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the benzyl residue and one methyl group substituents occupies an equatorial position, and the second methyl substituent occupies an axial position. The dihedral angle formed between the chlorobenzene ring and the flanking phenyl rings in molecule A are 84.24 (9) and 24.85 (8)°; the equivalent angles for molecule B are 79.97 (9) and 28.33 (9)°. In the crystal, the A and B molecules are connected by C—H⋯Cl and C—H⋯π interactions, forming a supramolecular chain along [101]. International Union of Crystallography 2012-06-30 /pmc/articles/PMC3394077/ /pubmed/22798942 http://dx.doi.org/10.1107/S1600536812029212 Text en © Ramalingan et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Ramalingan, Chennan Ng, Seik Weng Tiekink, Edward R. T. 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title | 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title_full | 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title_fullStr | 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title_full_unstemmed | 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title_short | 1-(2-Chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
title_sort | 1-(2-chlorobenzyl)-3,5-dimethyl-2,6-diphenylpiperidine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394077/ https://www.ncbi.nlm.nih.gov/pubmed/22798942 http://dx.doi.org/10.1107/S1600536812029212 |
work_keys_str_mv | AT ramalinganchennan 12chlorobenzyl35dimethyl26diphenylpiperidine AT ngseikweng 12chlorobenzyl35dimethyl26diphenylpiperidine AT tiekinkedwardrt 12chlorobenzyl35dimethyl26diphenylpiperidine |