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1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine

Two independent mol­ecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the...

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Autores principales: Ramalingan, Chennan, Ng, Seik Weng, Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394077/
https://www.ncbi.nlm.nih.gov/pubmed/22798942
http://dx.doi.org/10.1107/S1600536812029212
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author Ramalingan, Chennan
Ng, Seik Weng
Tiekink, Edward R. T.
author_facet Ramalingan, Chennan
Ng, Seik Weng
Tiekink, Edward R. T.
author_sort Ramalingan, Chennan
collection PubMed
description Two independent mol­ecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the benzyl residue and one methyl group substituents occupies an equatorial position, and the second methyl substituent occupies an axial position. The dihedral angle formed between the chloro­benzene ring and the flanking phenyl rings in mol­ecule A are 84.24 (9) and 24.85 (8)°; the equivalent angles for mol­ecule B are 79.97 (9) and 28.33 (9)°. In the crystal, the A and B mol­ecules are connected by C—H⋯Cl and C—H⋯π inter­actions, forming a supra­molecular chain along [101].
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spelling pubmed-33940772012-07-13 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine Ramalingan, Chennan Ng, Seik Weng Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers Two independent mol­ecules (A and B) comprise the asymmetric unit of the title compound, C(26)H(28)ClN, with the inverted form of B almost superimposable upon A. Each piperidine ring has a chair conformation and the chloro substituent is anti to the piperidine N atom. Each of two aromatic rings, the benzyl residue and one methyl group substituents occupies an equatorial position, and the second methyl substituent occupies an axial position. The dihedral angle formed between the chloro­benzene ring and the flanking phenyl rings in mol­ecule A are 84.24 (9) and 24.85 (8)°; the equivalent angles for mol­ecule B are 79.97 (9) and 28.33 (9)°. In the crystal, the A and B mol­ecules are connected by C—H⋯Cl and C—H⋯π inter­actions, forming a supra­molecular chain along [101]. International Union of Crystallography 2012-06-30 /pmc/articles/PMC3394077/ /pubmed/22798942 http://dx.doi.org/10.1107/S1600536812029212 Text en © Ramalingan et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ramalingan, Chennan
Ng, Seik Weng
Tiekink, Edward R. T.
1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title_full 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title_fullStr 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title_full_unstemmed 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title_short 1-(2-Chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
title_sort 1-(2-chloro­benz­yl)-3,5-dimethyl-2,6-diphenyl­piperidine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394077/
https://www.ncbi.nlm.nih.gov/pubmed/22798942
http://dx.doi.org/10.1107/S1600536812029212
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AT ngseikweng 12chlorobenzyl35dimethyl26diphenylpiperidine
AT tiekinkedwardrt 12chlorobenzyl35dimethyl26diphenylpiperidine