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Myricetin Inhibits Islet Amyloid Polypeptide (IAPP) Aggregation and Rescues Living Mammalian Cells from IAPP Toxicity

The aggregation of the amyloidogenic polypeptide IAPP (Islet Amyloid Polypeptide, amylin) is believed to play a direct role in the death of pancreatic β-islet cells in type II diabetes. Preventing the initial aggregation event of IAPP is one strategy for slowing, and possibly preventing, the progres...

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Detalles Bibliográficos
Autores principales:	Zelus, Casey, Fox, Ayano, Calciano, Anastasia, Faridian, Bianca S, Nogaj, Luiza A, Moffet, David A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394101/ https://www.ncbi.nlm.nih.gov/pubmed/22792130 http://dx.doi.org/10.2174/1874091X01206010066

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