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Attenuation of 40S Ribosomal Subunit Abundance Differentially Affects Host and HCV Translation and Suppresses HCV Replication

For Hepatitis C virus (HCV), initiation of translation is cap-independently mediated by its internal ribosome entry site (IRES). Unlike other IRES-containing viruses that shut off host cap-dependent translation, translation of HCV coexists with that of the host. How HCV IRES-mediated translation is...

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Detalles Bibliográficos
Autores principales:	Huang, Jing-Ying, Su, Wen-Chi, Jeng, King-Song, Chang, Tien-Hsien, Lai, Michael M. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394201/ https://www.ncbi.nlm.nih.gov/pubmed/22792060 http://dx.doi.org/10.1371/journal.ppat.1002766

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