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Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria

BACKGROUND: Artemisinin-based combination therapy (ACT) is currently recommended as first-line treatment for uncomplicated malaria, but of concern, it has been observed that the effectiveness of the main artemisinin derivative, artesunate, has been diminished due to parasite resistance. This reducti...

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Detalles Bibliográficos
Autores principales:	Jamsen, Kris M, Duffull, Stephen B, Tarning, Joel, Lindegardh, Niklas, White, Nicholas J, Simpson, Julie A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394219/ https://www.ncbi.nlm.nih.gov/pubmed/22551019 http://dx.doi.org/10.1186/1475-2875-11-143

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