CSA: comprehensive comparison of pairwise protein structure alignments

CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contac...

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Detalles Bibliográficos
Autores principales: Wohlers, Inken, Malod-Dognin, Noël, Andonov, Rumen, Klau, Gunnar W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394275/
https://www.ncbi.nlm.nih.gov/pubmed/22553365
http://dx.doi.org/10.1093/nar/gks362
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author Wohlers, Inken
Malod-Dognin, Noël
Andonov, Rumen
Klau, Gunnar W.
author_facet Wohlers, Inken
Malod-Dognin, Noël
Andonov, Rumen
Klau, Gunnar W.
author_sort Wohlers, Inken
collection PubMed
description CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contact map overlap, PAUL, DALI and MATRAS. These and additional, uploaded alignments are compared using a number of quality measures and intuitive visualizations. CSA brings new insight into the structural relationship of the protein pairs under investigation and is a valuable tool for studying structural similarities. It is available at http://csa.project.cwi.nl.
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spelling pubmed-33942752012-07-30 CSA: comprehensive comparison of pairwise protein structure alignments Wohlers, Inken Malod-Dognin, Noël Andonov, Rumen Klau, Gunnar W. Nucleic Acids Res Articles CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contact map overlap, PAUL, DALI and MATRAS. These and additional, uploaded alignments are compared using a number of quality measures and intuitive visualizations. CSA brings new insight into the structural relationship of the protein pairs under investigation and is a valuable tool for studying structural similarities. It is available at http://csa.project.cwi.nl. Oxford University Press 2012-07 2012-05-02 /pmc/articles/PMC3394275/ /pubmed/22553365 http://dx.doi.org/10.1093/nar/gks362 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Wohlers, Inken
Malod-Dognin, Noël
Andonov, Rumen
Klau, Gunnar W.
CSA: comprehensive comparison of pairwise protein structure alignments
title CSA: comprehensive comparison of pairwise protein structure alignments
title_full CSA: comprehensive comparison of pairwise protein structure alignments
title_fullStr CSA: comprehensive comparison of pairwise protein structure alignments
title_full_unstemmed CSA: comprehensive comparison of pairwise protein structure alignments
title_short CSA: comprehensive comparison of pairwise protein structure alignments
title_sort csa: comprehensive comparison of pairwise protein structure alignments
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394275/
https://www.ncbi.nlm.nih.gov/pubmed/22553365
http://dx.doi.org/10.1093/nar/gks362
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