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Hippocampal Neurogenesis, Cognitive Deficits and Affective Disorder in Huntington's Disease

Huntington's disease (HD) is a neurodegenerative disorder caused by a tandem repeat expansion encoding a polyglutamine tract in the huntingtin protein. HD involves progressive psychiatric, cognitive, and motor symptoms, the selective pathogenesis of which remains to be mechanistically elucidate...

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Detalles Bibliográficos
Autores principales: Ransome, Mark I., Renoir, Thibault, Hannan, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394391/
https://www.ncbi.nlm.nih.gov/pubmed/22830053
http://dx.doi.org/10.1155/2012/874387