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Towards accurate detection and genotyping of expressed variants from whole transcriptome sequencing data

BACKGROUND: Massively parallel transcriptome sequencing (RNA-Seq) is becoming the method of choice for studying functional effects of genetic variability and establishing causal relationships between genetic variants and disease. However, RNA-Seq poses new technical and computational challenges comp...

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Detalles Bibliográficos
Autores principales:	Duitama, Jorge, Srivastava, Pramod K, Măndoiu, Ion I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394419/ https://www.ncbi.nlm.nih.gov/pubmed/22537301 http://dx.doi.org/10.1186/1471-2164-13-S2-S6

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