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Gene-carried hepatoma targeting complex induced high gene transfection efficiency with low toxicity and significant antitumor activity
BACKGROUND: The success of gene transfection is largely dependent on the development of a vehicle or vector that can efficiently deliver a gene to cells with minimal toxicity. METHODS: A liver cancer-targeted specific peptide (FQHPSF sequence) was successfully synthesized and linked with chitosan-li...
Autores principales: | Zhao, Qing-Qing, Hu, Yu-Lan, Zhou, Yang, Li, Ni, Han, Min, Tang, Gu-Ping, Qiu, Feng, Tabata, Yasuhiko, Gao, Jian-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394466/ https://www.ncbi.nlm.nih.gov/pubmed/22811604 http://dx.doi.org/10.2147/IJN.S30909 |
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