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Evidence for a Non-Catalytic Ion-Binding Site in Multiple RNA-Dependent RNA Polymerases
A high-affinity divalent cation-binding site located proximal to the catalytic center has been identified in several RNA-dependent RNA polymerases (RdRps), but the characteristics of such a site have not been systematically studied. Here, all available polymerase structures that follow the hand-like...
Autores principales: | Mönttinen, Heli A. M., Ravantti, Janne J., Poranen, Minna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394715/ https://www.ncbi.nlm.nih.gov/pubmed/22792374 http://dx.doi.org/10.1371/journal.pone.0040581 |
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