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Resistance to Paclitaxel in a Cisplatin-Resistant Ovarian Cancer Cell Line Is Mediated by P-Glycoprotein
The IGROVCDDP cisplatin-resistant ovarian cancer cell line is also resistant to paclitaxel and models the resistance phenotype of relapsed ovarian cancer patients after first-line platinum/taxane chemotherapy. A TaqMan low-density array (TLDA) was used to characterise the expression of 380 genes ass...
Autores principales: | Stordal, Britta, Hamon, Marion, McEneaney, Victoria, Roche, Sandra, Gillet, Jean-Pierre, O’Leary, John J., Gottesman, Michael, Clynes, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394717/ https://www.ncbi.nlm.nih.gov/pubmed/22792399 http://dx.doi.org/10.1371/journal.pone.0040717 |
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