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A Dual Polybasic Motif Determines Phosphoinositide Binding and Regulation in the P2X Channel Family

Phosphoinositides modulate the function of several ion channels, including most ATP-gated P2X receptor channels in neurons and glia, but little is known about the underlying molecular mechanism. We identified a phosphoinositide-binding motif formed of two clusters of positively charged amino acids l...

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Detalles Bibliográficos
Autores principales:	Bernier, Louis-Philippe, Blais, Dominique, Boué-Grabot, Éric, Séguéla, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394732/ https://www.ncbi.nlm.nih.gov/pubmed/22792379 http://dx.doi.org/10.1371/journal.pone.0040595

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