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The Inhibition of Anti-DNA Binding to DNA by Nucleic Acid Binding Polymers

Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus (SLE) and can mediate disease pathogenesis by the formation of immune complexes. Since blocking immune complex formation can attenuate disease manifestations, the effects of nucleic acid binding polymers (NABPs...

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Detalles Bibliográficos
Autores principales: Stearns, Nancy A., Lee, Jaewoo, Leong, Kam W., Sullenger, Bruce A., Pisetsky, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394750/
https://www.ncbi.nlm.nih.gov/pubmed/22808279
http://dx.doi.org/10.1371/journal.pone.0040862