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The potential of Fas ligand (apoptosis-inducing molecule) as an unconventional therapeutic target in type 1 diabetes
The development of type 1 diabetes (T1D) is driven by autoreactive T cells that attack and destroy the insulin-producing β-cells in pancreatic islets, forcing patients to take multiple daily insulin injections. Insulin therapy, however, is not a cure and diabetic patients often develop serious long-...
Autores principales: | Hamad, Abdel Rahim A.R, Arcara, Kristin, Uddin, Sophia, Donner, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395106/ https://www.ncbi.nlm.nih.gov/pubmed/22807927 http://dx.doi.org/10.3389/fimmu.2012.00196 |
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