A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients

Dysregulation of the antiviral immune response may contribute to autoimmune diseases. Here, we hypothesized that altered expression or function of MAVS, a key molecule downstream of the viral sensors RIG-I and MDA-5, may impair antiviral cell signalling and thereby influence the risk for systemic lu...

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Detalles Bibliográficos
Autores principales: Pothlichet, Julien, Niewold, Timothy B, Vitour, Damien, Solhonne, Brigitte, Crow, Mary K, Si-Tahar, Mustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395111/
https://www.ncbi.nlm.nih.gov/pubmed/21268286
http://dx.doi.org/10.1002/emmm.201000120

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