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The Key to Unlocking the Chemotherapeutic Potential of PPARγ Ligands: Having the Right Combination
Despite extensive preclinical evidence that peroxisome proliferator-activated receptor (PPAR)γ activation protects against tumourigenesis, results from a few clinical trials using PPARγ ligands as monotherapy show modest success. In spite of this, several groups reported exciting results with therap...
Autores principales: | Skelhorne-Gross, Graham, Nicol, Christopher J. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395155/ https://www.ncbi.nlm.nih.gov/pubmed/22966225 http://dx.doi.org/10.1155/2012/946943 |
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