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Inhibition of follicular T helper cells by CD8(+) Treg is essential for self tolerance
The ability to produce vigorous immune responses that spare self tissues and organs depends on elimination of autoreactive T and B cells. However, purging of immature and mature self-reactive T and B cells is incomplete and may require additional censorship by cells programmed to suppress immune res...
Autores principales: | Kim, Hye-Jung, Verbinnen, Bert, Tang, Xiaolei, Lu, Linrong, Cantor, Harvey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395240/ https://www.ncbi.nlm.nih.gov/pubmed/20844537 http://dx.doi.org/10.1038/nature09370 |
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