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The Chemical Interplay between Nitric Oxide and Mitochondrial Cytochrome c Oxidase: Reactions, Effectors and Pathophysiology
Nitric oxide (NO) reacts with Complex I and cytochrome c oxidase (CcOX, Complex IV), inducing detrimental or cytoprotective effects. Two alternative reaction pathways (PWs) have been described whereby NO reacts with CcOX, producing either a relatively labile nitrite-bound derivative (CcOX-NO(2) (−)...
Autores principales: | Sarti, Paolo, Forte, Elena, Giuffrè, Alessandro, Mastronicola, Daniela, Magnifico, Maria Chiara, Arese, Marzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395247/ https://www.ncbi.nlm.nih.gov/pubmed/22811713 http://dx.doi.org/10.1155/2012/571067 |
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