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Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit

Abstract: Advances in swept source laser technology continues to increase the imaging speed of swept-source optical coherence tomography (SS-OCT) systems. These fast imaging speeds are ideal for microvascular detection schemes, such as speckle variance (SV), where interframe motion can cause severe...

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Autores principales: Lee, Kenneth K. C., Mariampillai, Adrian, Yu, Joe X. Z., Cadotte, David W., Wilson, Brian C., Standish, Beau A., Yang, Victor X. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395481/
https://www.ncbi.nlm.nih.gov/pubmed/22808428
http://dx.doi.org/10.1364/BOE.3.001557
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author Lee, Kenneth K. C.
Mariampillai, Adrian
Yu, Joe X. Z.
Cadotte, David W.
Wilson, Brian C.
Standish, Beau A.
Yang, Victor X. D.
author_facet Lee, Kenneth K. C.
Mariampillai, Adrian
Yu, Joe X. Z.
Cadotte, David W.
Wilson, Brian C.
Standish, Beau A.
Yang, Victor X. D.
author_sort Lee, Kenneth K. C.
collection PubMed
description Abstract: Advances in swept source laser technology continues to increase the imaging speed of swept-source optical coherence tomography (SS-OCT) systems. These fast imaging speeds are ideal for microvascular detection schemes, such as speckle variance (SV), where interframe motion can cause severe imaging artifacts and loss of vascular contrast. However, full utilization of the laser scan speed has been hindered by the computationally intensive signal processing required by SS-OCT and SV calculations. Using a commercial graphics processing unit that has been optimized for parallel data processing, we report a complete high-speed SS-OCT platform capable of real-time data acquisition, processing, display, and saving at 108,000 lines per second. Subpixel image registration of structural images was performed in real-time prior to SV calculations in order to reduce decorrelation from stationary structures induced by the bulk tissue motion. The viability of the system was successfully demonstrated in a high bulk tissue motion scenario of human fingernail root imaging where SV images (512 × 512 pixels, n = 4) were displayed at 54 frames per second.
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spelling pubmed-33954812012-07-17 Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit Lee, Kenneth K. C. Mariampillai, Adrian Yu, Joe X. Z. Cadotte, David W. Wilson, Brian C. Standish, Beau A. Yang, Victor X. D. Biomed Opt Express Optical Coherence Tomography Abstract: Advances in swept source laser technology continues to increase the imaging speed of swept-source optical coherence tomography (SS-OCT) systems. These fast imaging speeds are ideal for microvascular detection schemes, such as speckle variance (SV), where interframe motion can cause severe imaging artifacts and loss of vascular contrast. However, full utilization of the laser scan speed has been hindered by the computationally intensive signal processing required by SS-OCT and SV calculations. Using a commercial graphics processing unit that has been optimized for parallel data processing, we report a complete high-speed SS-OCT platform capable of real-time data acquisition, processing, display, and saving at 108,000 lines per second. Subpixel image registration of structural images was performed in real-time prior to SV calculations in order to reduce decorrelation from stationary structures induced by the bulk tissue motion. The viability of the system was successfully demonstrated in a high bulk tissue motion scenario of human fingernail root imaging where SV images (512 × 512 pixels, n = 4) were displayed at 54 frames per second. Optical Society of America 2012-06-07 /pmc/articles/PMC3395481/ /pubmed/22808428 http://dx.doi.org/10.1364/BOE.3.001557 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Optical Coherence Tomography
Lee, Kenneth K. C.
Mariampillai, Adrian
Yu, Joe X. Z.
Cadotte, David W.
Wilson, Brian C.
Standish, Beau A.
Yang, Victor X. D.
Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title_full Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title_fullStr Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title_full_unstemmed Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title_short Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
title_sort real-time speckle variance swept-source optical coherence tomography using a graphics processing unit
topic Optical Coherence Tomography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395481/
https://www.ncbi.nlm.nih.gov/pubmed/22808428
http://dx.doi.org/10.1364/BOE.3.001557
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