Detection of mixed populations of wild-type and YMDD hepatitis B variants by pyrosequencing in acutely and chronically infected patients

BACKGROUND: Lamivudine (LAM) is associated with the highest known rate of resistance mutations among nucleotide analogs used to treat chronic hepatitis B virus (HBV) infection. Despite this, LAM continues in widespread use, especially in combination therapies. The primary LAM resistance mutation (rt...

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Detalles Bibliográficos
Autores principales: Mello, Francisco C A, Lago, Bárbara V, Lewis-Ximenez, Lia L, Fernandes, Carlos A, Gomes, Selma A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395561/
https://www.ncbi.nlm.nih.gov/pubmed/22672436
http://dx.doi.org/10.1186/1471-2180-12-96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395561/
https://www.ncbi.nlm.nih.gov/pubmed/22672436
http://dx.doi.org/10.1186/1471-2180-12-96

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