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Detection of mixed populations of wild-type and YMDD hepatitis B variants by pyrosequencing in acutely and chronically infected patients

BACKGROUND: Lamivudine (LAM) is associated with the highest known rate of resistance mutations among nucleotide analogs used to treat chronic hepatitis B virus (HBV) infection. Despite this, LAM continues in widespread use, especially in combination therapies. The primary LAM resistance mutation (rt...

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Detalles Bibliográficos
Autores principales:	Mello, Francisco C A, Lago, Bárbara V, Lewis-Ximenez, Lia L, Fernandes, Carlos A, Gomes, Selma A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395561/ https://www.ncbi.nlm.nih.gov/pubmed/22672436 http://dx.doi.org/10.1186/1471-2180-12-96

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