CED-10/Rac1 Regulates Endocytic Recycling through the RAB-5 GAP TBC-2

Rac1 is a founding member of the Rho-GTPase family and a key regulator of membrane remodeling. In the context of apoptotic cell corpse engulfment, CED-10/Rac1 acts with its bipartite guanine nucleotide exchange factor, CED-5/Dock180-CED-12/ELMO, in an evolutionarily conserved pathway to promote phag...

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Detalles Bibliográficos
Autores principales: Sun, Lin, Liu, Ou, Desai, Jigar, Karbassi, Farhad, Sylvain, Marc-André, Shi, Anbing, Zhou, Zheng, Rocheleau, Christian E., Grant, Barth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395619/
https://www.ncbi.nlm.nih.gov/pubmed/22807685
http://dx.doi.org/10.1371/journal.pgen.1002785

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